Property:Plant toxic effect details

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Pages using the property "Plant toxic effect details"

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A
Azadirachta indica +	Large doses of Neem seeds are reported to have toxic effects on children. No effects have been found in adults.  +
B
Barleria prionitis +	Anti-spermatogenic at high doses  +
C
Cedrus deodara +	avoid Cedarwood oil during pregnancy  +
Ceratopteris thalictroides +	Excessive intake may cause cancer.  +
Crocus sativus +	Daily doses up to 1.5 g is safe, doses > 10 g can cause abortion  +
Curcuma longa +	Excessive turmeric intake has been documented to stimulate menstruation and cause abortion. Despite several clinical trials performed, not a lot of adverse reactions have been reported, except for rare cases of contact dermatitis and anaphylaxis. An increased risk of kidney stones is possible in susceptible individuals. No reports of toxicity have been reported following ingestion of large amounts of turmeric. Turmeric may cause stomach upset upon large scale ingestion. Nausea/Diarrhoea have been reported. Curcumin not advised for people with gallstones as one report shows it may cause gallbladder squeezing. Not to be consumed in large amounts by people with immune system deficiencies or with hypoglycemic blood.  +
G
Glycyrrhiza glabra +	The most widely reported side effects of glycyrrhizin use are hypertension and edema (water retention). These effects are related to the inhibition of cortisol metabolism within the kidney, and the subsequent stimulation of the mineralocorticoid receptors. Thus, consumption of black licorice can mimic disorders of excess aldosterone. Large doses of glycyrrhizinic acid and glycyrrhetinic acid in liquorice extract can lead to hypokalemia and serious increases in blood pressure, a syndrome known as apparent mineralocorticoid excess. These side effects stem from the inhibition of the enzyme 11β-hydroxysteroid dehydrogenase (type 2) and subsequent increase in activity of cortisol on the kidney. 11β-hydroxysteroid dehydrogenase normally inactivates cortisol in the kidney; thus, liquorice's inhibition of this enzyme makes the concentration of cortisol appear to increase. Cortisol acts at the same receptor as the hormone aldosterone in the kidney and the effects mimic aldosterone excess, although aldosterone remains low or normal during liquorice overdose. To decrease the chances of these serious side effects, deglycyrrhizinated liquorice preparations are available. The disabling of similar enzymes in the gut by glycyrrhizinic acid and glycyrrhetinic acid also causes increased mucus and decreased acid secretion. It inhibits Helicobacter pylori, is used as an aid for healing stomach and duodenal ulcers, and in moderate amounts may soothe an upset stomach.  +
M
Murraya exotica +	In high doses, can be abortive. Pregnant females should avoid ingestion.  +
O
Ocimum tenuiflorum +	LD50 of the leaf extract in mice is 3.75g/kg, when provided intra-peritoneally.  +
R
Rauvolfia serpentina +	rauwolfia alkaloids are known to many of drugs like Brofaromine, Clorgyline, Furazolidone, Iproniazid, Isocarboxazid, Lazabemide, Linezolid, Moclobemide, Nialamide, Pargyline, Phenelzine, Procarbazine, Rasagiline, Selegiline, Tetrabenazine, Toloxatone, Tranylcypromine. These alkaloids can have various effects on many other medical complications, so a strict medical supervision is advisable while taking rauwolfia alkaloids. Strychnine is known to be toxic at high concentrations  +
Z
Zingiber officinale +	High dosage may cause side-effects in pregnant women. It is also known to cause allergies in some people (Kew). Ginger is contraindicated in people suffering from gallstones as it promotes the production of bile (Wikipedia).  +